tanshinoneⅡA相关论文
Sodium Tanshinone ⅡA Sulfonate for Coronary Heart Disease:A Systematic Review of Randomized Controll
Objective:To assess whether an adjunctive therapy of Sodium Tanshinone ⅡA Sulfonate Injection (STS) is effective and sa......
Tanshinone Ⅱ A Protects against Lipopolysaccharides-Induced Endothelial Cell Injury via Rho/Rho Kina
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Tanshinone ⅡA Inhibits Dendritic Cell-mediated Adaptive Immunity: Potential Role in Anti-atheroscler
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Sodium Tanshinone ⅡA Sulfonate Ameliorates Microcirculatory Disturbance of Small Intestine by Attenu
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Due to ineffectiveness and side effects of existing analgesics, chronic pain has become one of the most complex and diff......
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Enrichment and Purification of Tanshinone ⅡA from Salvia miltiorrhiza Bunge Extracts with Macroporou
Tanshinone ⅡA,one of the most important components of Salvia miltiorrhiza Bunge,can be used for the treatment of cardio......
Background:Tendon adhesion between the sheath and tendon surface is a common clinical problem....
Glycyrrhetinic Acid-Decorated and Reduction-Sensitive Micelles for Enhancing Bioavailability and Ant
In the present study, we developed a dual-functional biodegradable micellar system named glycyrrhetinic acid-poly (ethyl......
Tanshinone Ⅱ A, the major lipophilic component of Danshen, promotes neuronal differentiation through
Danshen has been used in stroke treatment for thousands of years in China.However, the underlying mechanism still remain......
Inflammation takes responsibility for the seawater aspiration-induced lung injury.Tanshinone ⅡA (TⅡA) can protect lipo......
Tanshinone ⅡA suppresses lung injury and apoptosis and modulates AKT and ERK pathways in rats challe
1.Tanshinone ⅡA (TⅡA) is one of the main active components of the Chinese herb Danshen.In this study, we investigated ......
Tanshinone ⅡA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and
Aquaporins (AQPs), a family of transmembrane water channels, mediate physiological response to changes of fluid volume a......
The Washout with UW Solution and Tanshinone IIA to Decrease Ischemia Reperfusion Injury in Rat Ische
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Tanshinone Ⅱ A (T Ⅱ A) is widely used for the treatment of various human diseases including diabetic nephropathy (DN)1......
Efficacy and mechanism of tanshinone ⅡA liquid nanoparticles in preventing experimental postoperativ
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Tanshinone ⅡA protects Schwann cells apoptosis in mitochondrial pathway induced by intermittent high
Objective: To investigate the protective effects of Tanshinone ⅡA (Tan ⅡA) on Schwann cells (SCs) mitochondrial apopto......
Tanshinone ⅡA protects H9c2 cells from oxidative stress-induced cell death via up-regulation ofmicro
In this study the cardioprotective effect and molecular mechinsms of tanshinone ⅡA were investigated.Results showed tha......
Tanshinone ⅡA Induces Apoptosis of Cervical Cancer HeLa Cells and Advanced CaSki Cell with Proteomic
Objective Cervical cancer is one of the most common causes of mortality to females in the world.At present, paclitaxel (......
Tanshinone ⅡA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehy
Metabolic reprogramming is associated with NLRP3 inflammasome activation in activated macrophages,contributing to inflam......
The Molecular Mechanisms of Tanshinone Ⅱ A on the Apoptosis and Arrest of Human Esophageal Carcinoma
Tanshinone Ⅱ A (Tan Ⅱ A) is a monomer isolated from Salvia miltiorrhiza Bunge (Danshen) with anti-cancer effects r......
目的观察乙酰丹参酮ⅡA(ATA)对人卵巢癌细胞增殖和凋亡的诱导作用及对雌激素诱发蛋白TFF1表达的影响,探讨可能的作用机制。方法通......
目的:研究丹参酮ⅡA抑制迁移以及新生血管形成的作用机制.方法:通过MTT,2-D/3-D迁移,血管生成,PCR,CAM等方法,评价丹参酮ⅡA抑制肿......
目的探讨鞘内注射丹参酮ⅡA对骨癌痛小鼠热痛觉过敏及脊髓水平白介素-1β(IL-1β)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)表达......
Tanshinone ⅡA improves distribution and anti-tumor efficacy of pegylated liposomal doxorubicin via n
OBJECTIVE:To investigate whether the Tan Ⅱ A could improve the distribution and anti-tumor efficacy of Pegylated Liposo......
Bone Marrow-Derived Mesenchymal Stem Cells Incubated with Tanshinone IIA Aattenuates Learning and Me
Objective:The present study was designed to investigate the neuroprotective effect of mesenchymal stem cells(MSC)which i......
目的 研究丹参酮Ⅱ A(tanshinone Ⅱ A,TSN)对大鼠.肾间质成纤维细胞转化生长因子β1(transforming growth factor β1,TGFlβ1)信......
目的 研究人参皂苷Rg1配伍丹参酮ⅡA对缺氧-复氧H9c2细胞的保护作用及机制.方法 培养H9c2细胞并分为空白对照组(DMEM处理、常规条......
目的 探讨水通道蛋白5(AQP5)在海水浸泡致细胞损伤中的变化,同时了解丹参酮Ⅱ A可能的作用机制.方法 体外传代培养肺腺癌细胞株A54......
目的研究丹参酮ⅡA对氧化三甲胺(TMAO)诱导的人脐静脉内皮细胞炎症损伤的抑制作用,探讨其对TMAO诱导动脉粥样硬化(AS)的治疗作用及......
The Effect of Tanshinone Ⅱ A upon the TGF-beta1/Smads Signaling Pathway in Hypertrophic Myocardium o
SN Ⅱ A on TGF betal/Smads signal pathway in local myocardium....
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Fufang Danshen preparation (FDP) is consisted of Salviae Miltiorrhizar Radix et Rhizoma (Danshen),Notoginseng Radix et R......
目的:建立测定治疣胶囊中丹参酮ⅡA和丹酚酸B的HPLC方法。方法:采用Waters Atlantis@T3色谱柱(150 mm×4.6 mm,3μm),以乙腈-醋酸......
目的探讨丹参酮ⅡA(TSA)固体分散体制备、表征和体外溶出情况,分析其体外溶出特性。方法利用固体分散技术制备丹参酮ⅡA-PVP固体分......
目的探讨丹参酮ⅡA通过转录因子NF-E2相关因子2(Nrf2)通路对自发性高血压大鼠(SHR)的疗效及血管活性物质的影响。方法15只健康雄性......
目的探讨丹参酮ⅡA(TA)和丹酚酸(SA)B联合用药对成纤维细胞转化的影响。方法Transwell小室法检测TA和SAB对血管紧张素(Ang)Ⅱ诱导......
用乙醇回流提取法以丹参中丹参酮ⅡA含量为指标优化提取工艺。在单因素实验的基础上,对温度、料液比、浸泡时间、回流时间4个因素......
通过建立双侧颈总动脉结扎(BCCAO)大鼠模型和H_2O_2诱导的原代星形胶质细胞的氧化损伤模型,探究丹参酮ⅡA(TSA)的神经保护作用和机......
以丹参为原料,采用95%乙醇水溶液为溶剂提取丹参酮ⅡA。在不同丹参颗粒粒径及不同温度下对丹参酮ⅡA的传质动力学进行了研究。基于......
This study examined the effect of tanshinoneⅡA (TSNⅡA) on the cardiac fibrosis induced by transforming growth factor ......
目的建立丹黄胶囊的质量标准,为其质控提供依据。方法采用薄层色谱(TLC)法对制剂中的丹参、川芎、五味子和黄芪四味药材进行定性鉴别......
目的探讨丹参酮ⅡA(TanⅡA)对膀胱癌细胞体内增殖的影响以及相关机制。方法将膀胱癌T24细胞注射到20只裸鼠皮下,建立裸鼠膀胱癌动......
目的观察丹参酮Ⅱa对HL-60的凋亡与自噬以及相关因子水平的影响,探讨丹参酮Ⅱa抗急性髓系白血病的分子机制。方法使用不同浓度的丹......
采用正交实验法,以提取物中丹参酮ⅡA的含量为指标进行正交实验。所得产品中丹参酮ⅡA含量符合《药典》标准。从而优选出从丹参中提......
目的:采用高效液相色谱法测定组方中主药丹参所含药理活性成分丹参酮ⅡA的含量。方法:色谱柱:C1(8DaisoSp-120-5-ODS-AP4.6×250mm......
目的:研究丹参酮ⅡA对脓毒症大鼠急性肝肾损伤的治疗作用。方法:采用中线剖腹手术和盲肠结扎穿孔法将大鼠随机分为4组:假手术组(CT......
目的:基于网络药理学分析丹参酮ⅡA治疗脊髓损伤的分子生物学机制及相关通路。方法:利用TCMSP、BATMAN-TCM、DTPS、STITCHI、Swiss......
目的:探讨丹参酮ⅡA(STS)对脓毒症小鼠脑微血流和神经炎症反应的干预作用。方法:32只昆明小鼠常规开颅窗后随机分成4组:假手术组(Sham组)......